The course is the Devil's Dome Loop, a 45 mile loop linking the Jackita Ridge Trail, Devil's Dome Trail, and Eastbank Trail, which offers runners and hikers a small taste of the Paseyton Wilderness, some of the wildest country left in the continental United States. By our reckoning, it's about 10,000 feet of climbing. But be forewarned, the 12 miles along the East Bank Trail and the 3 miles along Ruby Creek have very little elevation gain. So the vast majority of that 10,000 feet of climbing takes place over only 30 miles of the route.
The Devil's Dome Loop is accessed from the North Cascades Highway (Washington State Route 20) via the East Bank Trailhead (milepost 138.2) or the Canyon Creek Trailhead (milepost 141.2). Choice of clockwise or counterclockwise is up to participants. Trips may started at any point on the loop, as long as that same point is returned to in order to complete an entire loop.